Article
Characterization of Osh3, an oxysterol-binding protein, in filamentous growth of Saccharomyces cerevisiae and Candida albicans.
Journal of microbiology (Seoul, Korea) - 1 Oct 2006
Hur Hyang-sook, Ryu Ji-Ho, Kim Kwang-Hoon, Kim Jinmi
Abstract excerpt
OSH3 is one of the seven yeast homologues of the oxysterol binding proteins (OSBPs) which have the major binding affinity to the oxysterols and function as regulator of cholesterol biosynthesis in mammals. Mutational analysis of OSH3 showed that OSH3 plays a regulatory role in the yeast-to-hyphal transition through its oxysterol-binding domain in Saccharomyces cerevisiae. The OSH3 gene was also identified in the...
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