Article
[Establishing the linkage disequilibrium pattern for the all-trans-retinol dehydrogenase (RDH8) gene].
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology - 1 Jul 2006
Han Wei, Shen Ye, Wang Jing, Yip Sheaping, Yap Maurice K H
Abstract excerpt
OBJECTIVE: As part of an on-going effort to map genes involved in complex eye diseases, myopia in particular, single nucleotide polymorphisms (SNPs) and linkage disequilibrium (LD) pattern were used to identified the gene within and around the All-trans-retinol dehydrogenase (RDH8). METHODS: Denaturing high-performance liquid chromatography (DHPLC) was used to screen SNPs in 4 DNA pools each consisting of DNA...
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