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Article

[Application of DHPLC in human genomic SNP screening and genotyping for all-trans-retinol dehydrogenase].

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences - 1 May 2005

Han Wei, Lou Ding-hua, Wang Jing, Yip Sheaping, Yap Mauric

Abstract excerpt

OBJECTIVE: To assess the efficacy of denaturing high-performance liquid chromatography (DHPLC) as a new screening assay for sequence variation in SNP detecting and new approach to SNP genotyping. METHODS: DHPLC was used to screen SNPs in 8 DNA pools each consisting of DNA from 5 individuals, and genotype the identified SNPs in 150 Chinese subjects from Hong Kong. RESULTS: Seventeen SNPs were identified: 12 were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 15940794
DOI: 10.3785/j.issn.1008-9292.2005.03.012

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MAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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