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Article

MyoD expression restores defective myogenic differentiation of human mesoangioblasts from inclusion-body myositis muscle

2 Nov 2006

Abstract excerpt

Inflammatory myopathies (IM) are acquired diseases of skeletal muscle comprising dermatomyositis (DM), polymyositis (PM), and inclusion-body myositis (IBM). Immunosuppressive therapies, usually beneficial for DM and PM, are poorly effective in IBM. We report the isolation and characterization of mesoangioblasts, vessel-associated stem cells, from diagnostic muscle biopsies of IM. The number of cells isolated,...

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PMID: 17077152
DOI: 10.1073/pnas.0603386103

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