Article
Sequence diversity of the mucABD locus in Pseudomonas aeruginosa isolates from patients with cystic fibrosis.
Microbiology (Reading, England) - 1 Nov 2006
Bragonzi Alessandra, Wiehlmann Lutz, Klockgether Jens, Cramer Nina, Worlitzsch Dieter, Döring Gerd, Tümmler Burkhard
Abstract excerpt
The mucA gene of the muc operon, which is instrumental in the control of the biosynthesis of the exopolysaccharide alginate, is a hotspot of mutation in Pseudomonas aeruginosa, a micro-organism that chronically colonizes the airways of individuals with cystic fibrosis (CF). The mucA, mucB and muc...
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