Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Development of a Drosophila seizure model for in vivo high-throughput drug screening.

The European journal of neuroscience - 1 Oct 2006

Stilwell Geoff E, Saraswati Sudipta, Littleton J Troy, Chouinard Scott W

Abstract excerpt

An important application of model organisms in neurological research has been to identify and characterise therapeutic approaches for epilepsy, a recurrent seizure disorder that affects > 1% of the human population. Proconvulsant-treated rodent models have been widely used for antiepileptic drug...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anticonvulsants
Share to Drug Evaluation, Preclinical
Share to Electrophysiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GABA Antagonists

Share to Pentylenetetrazole

Share to Phenytoin

Share to Seizures

Source

Identifiers

PMID: 17074045
DOI: 10.1111/j.1460-9568.2006.05075.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17074045-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Development of a Drosophila seizure model for in vivo high-throughput drug screening.PMID 17074045Read ↗

Toward the use of novel alternative methods in epilepsy modeling and drug discoverySemantic proximity Read ↗

Zebrafish as an Innovative Tool for Epilepsy Modeling: State of the Art and Potential Future DirectionsSemantic proximity Read ↗

Seizure-suppressor genes: can they help spearhead the discovery of novel therapeutic targets for epilepsy?Semantic proximity Read ↗

Clemizole and Trazodone are Effective Antiseizure Treatments in a Zebrafish Model of STXBP1 DisorderSemantic proximity Read ↗

Phenotype-based screening of synthetic cannabinoids in a Dravet Syndrome zebrafish modelSemantic proximity Read ↗

Testing of putative antiseizure medications in a preclinical Dravet syndrome zebrafish modelSemantic proximity Read ↗

Phenotype-Based Screening of Synthetic Cannabinoids in a Dravet Syndrome Zebrafish ModelSemantic proximity Read ↗

Testing of putative antiseizure drugs in a preclinical Dravet syndrome zebrafish modelSemantic proximity Read ↗

Characterization of induction methods for <i>Drosophila</i> seizure mutationsSemantic proximity Read ↗

A large-scale mutagenesis screen to identify seizure-resistant zebrafish.Semantic proximity Read ↗

Drosophila expressing mutant human KCNT1 transgenes make an effective tool for targeted drug screening in a whole animal model of KCNT1-epilepsy.Semantic proximity Read ↗

Seizure and epilepsy: studies of seizure disorders in Drosophila.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.