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Article

Unexpected development of autoimmunity in BAFF-R-mutant MRL-lpr mice.

Immunology - 1 Feb 2007

Ju Zhong L, Shi Gui Y, Zuo Jin X, Zhang Jing W

Abstract excerpt

BAFF-R is the predominant receptor that mediates B-cell activating factor (BAFF)-dependent B-cell signalling and plays a critical role in late-stage B-cell maturation and survival. BAFF has been implicated in the development of autoimmunity and systemic lupus erythematosus (SLE). To define the role of BAFF-R in autoimmunity and SLE, we crossed A/WySnJ mice with MRL-lpr mice and generated BAFF-R-mutant MRL-lpr...

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Identifiers

PMID: 17073941
DOI: 10.1111/j.1365-2567.2006.02500.x
PMCID: PMC2265857

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Unexpected development of autoimmunity in BAFF-R-mutant MRL-lpr mice.PMID 17073941Read ↗

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