Article
Diversity and evolution of cytochrome P450 monooxygenases in Oomycetes.
Scientific reports - 1 Jul 2015
Sello Mopeli Marshal, Jafta Norventia, Nelson David R, Chen Wanping, Yu Jae-Hyuk, Parvez Mohammad, Kgosiemang Ipeleng Kopano Rosinah, Monyaki Richie, Raselemane Seiso Caiphus, Qhanya Lehlohonolo Benedict, Mthakathi Ntsane Trevor, Sitheni Mashele Samson, Syed Khajamohiddin
Abstract excerpt
Cytochrome P450 monooxygenases (P450s) are heme-thiolate proteins whose role as drug targets against pathogens, as well as in valuable chemical production and bioremediation, has been explored. In this study we performed comprehensive comparative analysis of P450s in 13 newly explored oomycete pathogens. Three hundred and fifty-six P450s were found in oomycetes. These P450s were grouped into 15 P450 families and...
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