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Article

Origins of P450 diversity.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 19 Feb 2013

Sezutsu Hideki, Le Goff Gaëlle, Feyereisen René

Abstract excerpt

The P450 enzymes maintain a conserved P450 fold despite a considerable variation in sequence. The P450 family even includes proteins that lack the single conserved cysteine and are therefore no longer haem-thiolate proteins. The mechanisms of successive gene duplications leading to large families in plants and animals are well established. Comparisons of P450 CYP gene clusters in related species illustrate the...

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Identifiers

PMID: 23297351
DOI: 10.1098/rstb.2012.0428
PMCID: PMC3538418

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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