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Article

Murine osteoblasts respond to LPS and IFN-gamma similarly to macrophages.

Journal of bone and mineral metabolism - 1 Jan 2006

Maruyama Kenta, Sano Gen-Ichiro, Matsuo Koichi

Abstract excerpt

Osteoblasts are bone-forming mesenchymal cells, while macrophages are cells of hematopoietic origin responsible for innate immunity. Lipopolysaccharide (LPS) can induce tolerance in macrophages, whereas interferon (IFN)-gamma can activate macrophages to produce cytokines, exert bactericidal effects, and present antigens. In this study, we examined such macrophagic phenotypes regulated by LPS and IFN-gamma in...

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Identifiers

PMID: 17072737
DOI: 10.1007/s00774-006-0708-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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