Article
Divergent evolution of a structural proteome: phenomenological models.
Biophysical journal - 1 Feb 2007
Roland C Brian, Shakhnovich Eugene I
Abstract excerpt
We develop models of the divergent evolution of genomes; the elementary object of sequence dynamics is the protein structural domain. To identify patterns of organization that reflect mechanisms of evolution, we consider the individual genomes of many procaryote species, studying the arrangement of protein structural domains in the space of all polypeptide structures. We view the network of structural...
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