Article
RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.
PLoS genetics - 1 Oct 2006
Aslanukov Azamat, Bhowmick Reshma, Guruju Mallikarjuna, Oswald John, Raz Dorit, Bush Ronald A, Sieving Paul A, Lu Xinrong, Bock Cheryl B, Ferreira Paulo A
Abstract excerpt
The Ran-binding protein 2 (RanBP2) is a large multimodular and pleiotropic protein. Several molecular partners with distinct functions interacting specifically with selective modules of RanBP2 have been identified. Yet, the significance of these interactions with RanBP2 and the genetic and physiological role(s) of RanBP2 in a whole-animal model remain elusive. Here, we report the identification of two novel...
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