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Comprehensive Bioinformatics Analysis Identifies POLR2I as a Key Gene in the Pathogenesis of Hypertensive Nephropathy

5 Aug 2021

Abstract excerpt

Hypertensive nephropathy (HN), mainly caused by chronic hypertension, is one of the major causes of end-stage renal disease. However, the pathogenesis of HN remains unclarified, and there is an urgent need for improved treatments. Gene expression profiles for HN and normal tissue were obtained from the Gene Expression Omnibus database. A total of 229 differentially co-expressed genes were identified by weighted...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34422001
DOI: 10.3389/fgene.2021.698570

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