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Article

Linkage analysis using sex-specific recombination fractions with GENEHUNTER-MODSCORE.

Bioinformatics (Oxford, England) - 1 Jan 2007

Dietter Johannes, Mattheisen Manuel, Fürst Robert, Rüschendorf Franz, Wienker Thomas F, Strauch Konstantin

Abstract excerpt

MOTIVATION: Sex-specific marker maps have become increasingly available. We have implemented the usage of sex-specific recombination frequencies in the GENEHUNTER-MODSCORE program that performs multipoint linkage analysis. Furthermore, we have devised a consistent method to choose the combinations of male and female genetic positions at which linkage scores should be calculated. Marker coordinates can be read...

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PMID: 17060360
DOI: 10.1093/bioinformatics/btl539

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