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Article

Vaccinia topoisomerase mutants illuminate roles for Phe59, Gly73, Gln69 and Phe215.

Virology - 15 Mar 2007

Tian Ligeng, Shuman Stewart

Abstract excerpt

Vaccinia topoisomerase provides a model system for structure-function analysis of the type IB topoisomerase family. Here we performed an alanine scan of eight positions in the beta4 and beta5 strands of the N-terminal domain (Leu57, Ile58, Phe59, Val60, Gly61, Ser62, Gln69 and Gly73) and eight po...

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Source

Identifiers

PMID: 17059840
DOI: 10.1016/j.virol.2006.08.056

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17059840-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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