Article
Cytokine gene polymorphisms and high-resolution-computed tomography score in idiopathic pulmonary fibrosis.
Respiratory medicine - 1 May 2007
Vasakova Martina, Striz Ilja, Dutka Juraj, Slavcev Antonij, Jandova Sarka, Kolesar Libor, Sulc Jan
Abstract excerpt
INTRODUCTION: Idiopathic pulmonary fibrosis (IPF) is a serious disease with unknown cause and the influence of cytokine gene polymorphisms is presumed in the etiology and pathogenesis of the disease. We used high-resolution computed tomography (HRCT) as a marker of disease stage and progression and compared the alveolar and interstitial score with IL-1, IL-4, IL-12, IL-1RA and IL-4RA cytokine gene polymorphisms....
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