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Article

Complementarity between epsilon and phi sequences in pregenomic RNA influences hepatitis B virus replication efficiency.

Virology - 15 Mar 2007

Oropeza Claudia E, McLachlan Alan

Abstract excerpt

Hepatitis B virus (HBV) replication requires the viral polymerase to reverse transcribe the 3.5-kb pregenomic viral RNA within the nucleocapsid. It has been proposed that a sequence element designated phi (phi), which is located 32 nucleotides upstream of the 3' DR1 pregenomic RNA sequence and is complementary to epsilon, is required for efficient minus-strand synthesis because it may mediate the translocation of...

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Identifiers

PMID: 17056086
DOI: 10.1016/j.virol.2006.08.036
PMCID: PMC1850982

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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