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Article

Perspectives on development of a combination pharmacogenomic diagnostic and drug product.

Pharmacogenomics - 1 Oct 2006

McCamish Mark, Izumi Raquel

Abstract excerpt

This perspective outlines the challenges to joint development of a predictive genetic diagnostic with a drug to enhance the efficacy or safety of therapy with the targeted drug. Joint development requires a discovery approach to identify the genetic marker(s), followed by a replication or validation process confirming the clinical utility of the genetic marker(s) in predicting response to the targeted drug. The...

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PMID: 17054414
DOI: 10.2217/14622416.7.7.1045

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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