Article
Characterization of genotype-specific epitopes of the HN protein of mumps virus.
The Journal of general virology - 1 Dec 1997
Orvell C, Alsheikhly A R, Kalantari M, Johansson B
Abstract excerpt
The SBL-1 strain of mumps virus, grouping with genotype A on the basis of the small hydrophobic protein gene sequence, was grown in the presence of three different monoclonal antibodies. The monoclonal antibodies were directed against the haemagglutinin-neuraminidase (HN) protein and they inhibited haemagglutinating activity and infectivity of the virus. The HN genes of the nine neutralization-escape virus...
Topics
- Amino Acid Sequence
- Animals
- Antigens, Viral
- Epitope Mapping
- Epitopes
- Genes, Viral
- Genotype
- HN Protein
- Mice
- Molecular Sequence Data
- Mumps virus
- Mutation
