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Article

GABAA receptors in epilepsy: Elucidating phenotypic divergence through functional analysis of genetic variants.

Journal of neurochemistry - 1 Dec 2024

Absalom Nathan L, Lin Susan X N, Liao Vivian W Y, Chua Han C, Møller Rikke S, Chebib Mary, Ahring Philip K

Abstract excerpt

Normal brain function requires a tightly regulated balance between excitatory and inhibitory neurotransmissions. γ-Aminobutyric acid type A (GABAA) receptors represent the major class of inhibitory ion channels in the mammalian brain. Dysregulation of these receptors and/or their associated pathways is strongly implicated in the pathophysiology of epilepsy. To date, hundreds of different GABAA receptor subunit...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 37621067
DOI: 10.1111/jnc.15932
PMCID: PMC11591409

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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