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Article

Mutant GABA(A) receptor subunits in genetic (idiopathic) epilepsy.

Progress in brain research - 1 Jan 2014

Hirose Shinichi

Abstract excerpt

The γ-aminobutyric acid receptor type A (GABAA receptor) is a ligand-gated chloride channel that mediates major inhibitory functions in the central nervous system. GABAA receptors function mainly as pentamers containing α, β, and either γ or δ subunits. A number of antiepileptic drugs have agonistic effects on GABAA receptors. Hence, dysfunctions of GABAA receptors have been postulated to play important roles in...

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Share to Epilepsy, Generalized
Share to GABRB3 gene
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, GABA-A

Source

Identifiers

PMID: 25194483
DOI: 10.1016/B978-0-444-63326-2.00003-X

Genes

GABRA1
GABRB2
GABRB3
GABRA6
GABRD
GABRG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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