Article
Accounting for linkage disequilibrium in genome scans for selection without individual genotypes: The local score approach.
Molecular ecology - 1 Jul 2017
Fariello María Inés, Boitard Simon, Mercier Sabine, Robelin David, Faraut Thomas, Arnould Cécile, Recoquillay Julien, Bouchez Olivier, Salin Gérald, Dehais Patrice, Gourichon David, Leroux Sophie, Pitel Frédérique, Leterrier Christine, SanCristobal Magali
Abstract excerpt
Detecting genomic footprints of selection is an important step in the understanding of evolution. Accounting for linkage disequilibrium in genome scans increases detection power, but haplotype-based methods require individual genotypes and are not applicable on pool-sequenced samples. We propose to take advantage of the local score approach to account for linkage disequilibrium in genome scans for selection,...
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