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Article

Cell size checkpoint control by the retinoblastoma tumor suppressor pathway.

PLoS genetics - 13 Oct 2006

Fang Su-Chiung, de los Reyes Chris, Umen James G

Abstract excerpt

Size control is essential for all proliferating cells, and is thought to be regulated by checkpoints that couple cell size to cell cycle progression. The aberrant cell-size phenotypes caused by mutations in the retinoblastoma (RB) tumor suppressor pathway are consistent with a role in size checkpoint control, but indirect effects on size caused by altered cell cycle kinetics are difficult to rule out. The...

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Identifiers

PMID: 17040130
DOI: 10.1371/journal.pgen.0020167
PMCID: PMC1599770

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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