Article
Sesn1 is a novel gene for left-right asymmetry and mediating nodal signaling.
Human molecular genetics - 15 Nov 2006
Peeters Hilde, Voz Marianne L, Verschueren Kristin, De Cat Bart, Pendeville Hélène, Thienpont Bernard, Schellens Ann, Belmont John W, David Guido, Van De Ven Wim J M, Fryns Jean-Pierre, Gewillig Marc, Huylebroeck Danny, Peers Bernard, Devriendt Koen
Abstract excerpt
Remarkable progress has been made in understanding the molecular mechanisms underlying left-right asymmetry in vertebrate animal models but little is known on left-right axis formation in humans. Previously, we identified SESN1 (also known as PA26) as a candidate gene for heterotaxia by positiona...
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