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Article

Genetic characterization of the dihydrofolate reductase gene of Pneumocystis jirovecii isolates from Portugal.

The Journal of antimicrobial chemotherapy - 1 Dec 2006

Costa Marina C, Esteves Francisco, Antunes Francisco, Matos Olga

Abstract excerpt

OBJECTIVES: The aim of the present study was to evaluate the genetic variation of Pneumocystis jirovecii dihydrofolate reductase (DHFR) gene in an immunocompromised Portuguese population and to investigate the possible association between DHFR genotypes and P. jirovecii pneumonia (PcP) prophylaxis with co-trimoxazole. METHODS: One hundred and thirty-eight P. jirovecii isolates were submitted to DHFR genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17038348
DOI: 10.1093/jac/dkl411

Genes

DHFR

Provenance

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