Article
Interactive effects of lifetime alcohol consumption and alcohol and aldehyde dehydrogenase polymorphisms on esophageal cancer risks.
International journal of cancer - 15 Dec 2006
Chen Yun-Ju, Chen Chu, Wu Deng-Chyang, Lee Chien-Hung, Wu Chen-I, Lee Jang-Ming, Goan Yih-Gang, Huang Shu-Pin, Lin Cheng-Chieh, Li Tsai-Chung, Chou Yi-Pin, Wu Ming-Tsang
Abstract excerpt
In our previous study, we found that polymorphisms of alcohol and aldehyde dehydrogenase (ADH1B and ALDH2) are important risks for esophageal squamous cell carcinoma in a Taiwanese population. In this study, we increased the sample size to investigate the modifying effect of lifetime alcohol consumption on the association between ADH1B and ALDH2 genotypes and the risks of esophageal cancer. A multicenter...
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