Article
Human cytomegalovirus infection alters PC3 prostate carcinoma cell adhesion to endothelial cells and extracellular matrix.
Neoplasia (New York, N.Y.) - 1 Oct 2006
Blaheta Roman A, Weich Eva, Marian Dana, Bereiter-Hahn Jürgen, Jones Jon, Jonas Dietger, Michaelis Martin, Doerr Hans Willhelm, Cinatl Jindrich
Abstract excerpt
The genome and antigens of human cytomegalovirus (HCMV) are frequently found in prostatic carcinoma. However, whether this infection is causative or is an epiphenomenon is not clear. We therefore investigated the ability of HCMV to promote metastatic processes, defined by tumor cell adhesion to the endothelium and extracellular matrix proteins. Experiments were based on the human prostate tumor cell line PC3,...
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