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Article

Adhesion of lymphocytes to bladder cancer cells: the role of the alpha(E)beta(7) integrin.

Cancer immunology, immunotherapy : CII - 1 Nov 2002

Cresswell Joanne, Wong Wai Keong, Henry Matthew J, Robertson Helen, Neal David E, Kirby John A

Abstract excerpt

The alpha(E)beta(7)integrin (defined by CD103) is expressed by most intra-epithelial lymphocytes (IEL) but by fewer than 2% peripheral blood lymphocytes (PBL). An important ligand for this molecule is the epithelial cell adhesion molecule E-cadherin. Loss of E-cadherin is associated with increased invasion and metastasis in bladder cancer. This study examines the role of the alpha(E)beta(7)-E-cadherin interaction...

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Share to Antigens, CD
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12357319
DOI: 10.1007/s00262-002-0305-3
PMCID: PMC11034297

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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