Article
Triglyceride associated polymorphisms of the APOA5 gene have very different allele frequencies in Pune, India compared to Europeans.
BMC medical genetics - 10 Oct 2006
Chandak Giriraj R, Ward Kirsten J, Yajnik Chittaranjan S, Pandit Anand N, Bavdekar Ashish, Joglekar Charu V, Fall Caroline H D, Mohankrishna P, Wilkin Terence J, Metcalf Bradley S, Weedon Michael N, Frayling Timothy M, Hattersley Andrew T
Abstract excerpt
BACKGROUND: The APOA5 gene variants, -1131T>C and S19W, are associated with altered triglyceride concentrations in studies of subjects of Caucasian and East Asian descent. There are few studies of these variants in South Asians. We investigated whether the two APOA5 variants also show similar association with various lipid parameters in Indian population as in the UK white subjects. METHODS: We genotyped 557...
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