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Article

DDD mice, a novel acute mouse model of Parkinson's disease.

Neurology - 10 Oct 2006

Sotnikova Tatyana D, Caron Marc G, Gainetdinov Raul R

Abstract excerpt

We describe the development of a novel animal model of acute severe dopamine (DA) deficiency by using genetically altered mice lacking the DA transporter (DAT-KO mice). In the absence of a DAT-mediated recycling mechanism in these mice, striatal DA concentrations become entirely dependent on its...

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Identifiers

PMID: 17030735
DOI: 10.1212/wnl.67.7_suppl_2.s12

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17030735-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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