Article
A common genetic variant in XPD associates with risk of 5q- and 7q-deleted acute myeloid leukemia.
Blood - 1 Feb 2007
Smith Alexandra G, Worrillow Lisa J, Allan James M
Abstract excerpt
Numerous structural genetic abnormalities observed in acute myeloid leukemia (AML) illustrate the heterogeneity of this disease, which likely has contributed to difficulty in identifying susceptibility alleles for AML. We previously reported that carriers of the glutamine-encoding allele at codon 751 of the xeroderma pigmentosum group D (XPD) DNA repair gene were significantly more likely to have a karyotype...
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