Article
Variation of interleukin 8 -251 A>T polymorphism in worldwide populations and intra-ethnic differences in Japanese populations.
Clinica chimica acta; international journal of clinical chemistry - 1 Feb 2007
Fujihara Junko, Shiwaku Kuninori, Yasuda Toshihiro, Yuasa Isao, Nishimukai Hiroaki, Iida Reiko, Takeshita Haruo
Abstract excerpt
BACKGROUND: Interleukin-8 (IL8) is a member of the family of chemokines. The IL8 gene has polymorphic variations, and the genotype of IL8 -251 A>T is associated with smoking behavior and cancer progression. METHOD: IL8 -251 A>T polymorphism were investigated in Japanese, from 5 different areas, in Ovambo, Turkish, Mongolian and Korean populations by PCR with confronting 2-pair primers (PCR-CTPP) analysis....
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