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Article

Replication of twelve association studies for Huntington's disease residual age of onset in large Venezuelan kindreds.

Journal of medical genetics - 1 Jan 2007

Andresen J M, Gayán J, Cherny S S, Brocklebank D, Alkorta-Aranburu G, Addis E A, Cardon L R, Housman D E, Wexler N S

Abstract excerpt

BACKGROUND: The major determinant of age of onset in Huntington's disease is the length of the causative triplet CAG repeat. Significant variance remains, however, in residual age of onset even after repeat length is factored out. Many genetic polymorphisms have previously shown evidence of association with age of onset of Huntington's disease in several different populations. OBJECTIVE: To replicate these...

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Source

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Identifiers

PMID: 17018562
DOI: 10.1136/jmg.2006.045153
PMCID: PMC2597910

Genes

TCERG1
GRIK2
APOE
DFFB
UCHL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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