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Article

Concerted mutation of Phe residues belonging to the beta-dystroglycan ectodomain strongly inhibits the interaction with alpha-dystroglycan in vitro.

The FEBS journal - 1 Nov 2006

Bozzi Manuela, Sciandra Francesca, Ferri Lorenzo, Torreri Paola, Pavoni Ernesto, Petrucci Tamara C, Giardina Bruno, Brancaccio Andrea

Abstract excerpt

The dystroglycan adhesion complex consists of two noncovalently interacting proteins: alpha-dystroglycan, a peripheral extracellular subunit that is extensively glycosylated, and the transmembrane beta-dystroglycan, whose cytosolic tail interacts with dystrophin, thus linking the F-actin cytoskeleton to the extracellular matrix. Dystroglycan is thought to play a crucial role in the stability of the plasmalemma,...

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Source

Identifiers

PMID: 17018058
DOI: 10.1111/j.1742-4658.2006.05492.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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