Article
Ezrin-dependent regulation of the actin cytoskeleton by beta-dystroglycan.
Human molecular genetics - 1 Aug 2004
Spence H J, Chen Y-J, Batchelor C L, Higginson J R, Suila H, Carpen O, Winder S J
Abstract excerpt
Dystroglycan is part of an adhesion receptor complex linking the extracellular matrix to the actin cytoskeleton. Previous studies have implicated dystroglycan in basement membrane formation and as a crucial link between dystrophin and laminin in muscle. We report here a further novel function for dystroglycan which appears to be in addition to its role as an adhesion molecule. beta-dystroglycan has been localized...
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