Article
An adhesion molecule involved in muscular dystrophies: structural and functional analysis of dystroglycan domains.
The Italian journal of biochemistry - 1 Mar 2003
Brancaccio Andrea
Abstract excerpt
Dystroglycan (DG) plays a pivotal role within the dystrophin-glycoprotein complex (DGC) which represents a major factor for muscle fibre stability upon contraction. It has been shown that many muscular dystrophy phenotypes are caused by mutations of proteins belonging to or being associated with the DGC. Due to its prominent role for muscle stability, the detailed knowledge of DG structural and functional aspects...
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