Article
The agrin/perlecan-related protein eyes shut is essential for epithelial lumen formation in the Drosophila retina.
Developmental cell - 1 Oct 2006
Husain Nicole, Pellikka Milena, Hong Henry, Klimentova Tsveta, Choe Kwang-Min, Clandinin Thomas R, Tepass Ulrich
Abstract excerpt
The formation of epithelial lumina is a fundamental process in animal development. Each ommatidium of the Drosophila retina forms an epithelial lumen, the interrhabdomeral space, which has a critical function in vision as it optically isolates individual photoreceptor cells. Ommatidia containing an interrhabdomeral space have evolved from ancestral insect eyes that lack this lumen, as seen, for example, in bees....
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