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Article

Molecular characterization of laforin, a dual-specificity protein phosphatase implicated in Lafora disease.

Biochimie - 1 Dec 2006

Girard Jean-Marie, Lê K H Diêp, Lederer Florence

Abstract excerpt

Lafora disease is a progressive myoclonus epilepsy with an early fatal issue. Two genes were identified thus far, the mutations of which cause the disease. The first one, EPM2A, encodes the consensus sequence of a protein tyrosine phosphatase. Its product, laforin, is the object of the present work. We analysed in detail the amino acid sequence of this protein. This suggested, as also observed by others, that it...

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Identifiers

PMID: 17010495
DOI: 10.1016/j.biochi.2006.08.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Molecular characterization of laforin, a dual-specificity protein phosphatase implicated in Lafora disease.PMID 17010495Read ↗

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