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Article

Relationship between glycogen accumulation and the laforin dual specificity phosphatase.

Biochemical and biophysical research communications - 24 Nov 2006

Wang Wei, Parker Gretchen E, Skurat Alexander V, Raben Nina, DePaoli-Roach Anna A, Roach Peter J

Abstract excerpt

Laforin, encoded by the EPM2A gene, is a dual specificity protein phosphatase that has a functional glycogen-binding domain. Mutations in the EPM2A gene account for around half of the cases of Lafora disease, an autosomal recessive neurodegenerative disorder, characterized by progressive myoclonu...

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Source

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Identifiers

PMID: 17022935
DOI: 10.1016/j.bbrc.2006.09.091
PMCID: PMC1850102

Genes

GAA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17022935-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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