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Article

ROCK signaling mediates the adoption of different modes of migration and invasion in human mammary epithelial tumor cells.

Experimental cell research - 15 Nov 2006

Torka Robert, Thuma Florian, Herzog Volker, Kirfel Gregor

Abstract excerpt

For the invasive migration of tumor cells, at least two mechanisms are currently discussed: (1) the mesenchymal mode depending on extracellular proteolysis and (2) the proteolysis-independent amoeboid mode depending on the activity of the Rho kinase ROCK. The ability of tumor cells to switch betw...

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Identifiers

PMID: 17010335
DOI: 10.1016/j.yexcr.2006.08.025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17010335-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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