Article
Cyclic AMP response element binding protein and brain-derived neurotrophic factor: molecules that modulate our mood?
Journal of biosciences - 1 Sept 2006
Nair A, Vaidya V A
Abstract excerpt
Depression is the major psychiatric ailment of our times, afflicting approximately 20% of the population. Despite its prevalence, the pathophysiology of this complex disorder is not well understood. In addition, although antidepressants have been in existence for the past several decades, the mechanisms that underlie their therapeutic effects remain elusive. Building evidence implicates a role for the plasticity...
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