Article
MultiCode-RTx real-time PCR system for detection of subpopulations of K65R human immunodeficiency virus type 1 reverse transcriptase mutant viruses in clinical samples.
Journal of clinical microbiology - 1 Nov 2006
Svarovskaia Evguenia S, Moser Michael J, Bae Andrew S, Prudent James R, Miller Michael D, Borroto-Esoda Katyna
Abstract excerpt
We report a real-time PCR assay capable of detecting drug-resistant human immunodeficiency virus type 1 reverse transcriptase K65R mutant virus at a level of 0.5% in polymorphic patient plasma specimens. Fifty-three treatment-naïve and 20 treatment-experienced specimens were successfully genotype...
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