Article
Genomic heterogeneity in the density of noncoding single-nucleotide and microsatellite polymorphisms in Plasmodium falciparum.
Gene - 31 Jan 2007
Volkman Sarah K, Lozovsky Elena, Barry Alyssa E, Bedford Trevor, Bethke Lara, Myrick Alissa, Day Karen P, Hartl Daniel L, Wirth Dyann F, Sawyer Stanley A
Abstract excerpt
The density and distribution of single-nucleotide polymorphisms (SNPs) across the genome has important implications for linkage disequilibrium mapping and association studies, and the level of simple-sequence microsatellite polymorphisms has important implications for the use of oligonucleotide hybridization methods to genotype SNPs. To assess the density of these types of polymorphisms in P. falciparum, we...
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