Article
Contribution of MHC class I region to genetic susceptibility for giant cell arteritis.
Rheumatology (Oxford, England) - 1 Mar 2007
Gonzalez-Gay M A, Rueda B, Vilchez J R, Lopez-Nevot M A, Robledo G, Ruiz M P, Fernández O, Garcia-Porrua C, Gonzalez-Escribano M F, Martín J
Abstract excerpt
OBJECTIVE: The aim of this study was to assess the potential contribution of HLA-class I MICA and HLA-B gene polymorphisms towards the pathogenesis of giant cell arteritis (GCA). METHODS: Ninety-eight biopsy-proven GCA patients and 225 ethnically matched controls from Lugo, Northwest Spain, were genotyped for the MICA-TM microsatellite polymorphism using a polymerase chain reaction (PCR)-based method. Genotyping...
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