The presence of both HLA-DRB1*04:01 and HLA-B*15:01 increases the susceptibility to cranial and extracranial giant cell arteritis.

doi:10.55563/clinexprheumatol/nn15lt

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Article

The presence of both HLA-DRB104:01 and HLA-B15:01 increases the susceptibility to cranial and extracranial giant cell arteritis.

Clinical and experimental rheumatology - 1 Jan 2000

Prieto-Peña Diana, Remuzgo-Martínez Sara, Ocejo-Vinyals Javier Gonzalo, Atienza-Mateo Belen, Genre Fernanda, Muñoz-Jimenez Alejandro, Ortiz-Sanjuán Francisco, Romero-Yuste Susana, Moriano Clara, Galindez-Agirregoikoa Eva, Calvo Itziar, Ortego-Centeno Norberto, Álvarez-Rivas Noelia, Miranda-Filloy José A, Llorente Irene, García-García Javier, Blanco Ricardo, Gualillo Oreste, Martin Javier, Castañeda Santos, Lopez-Mejías Raquel, González-Gay Miguel A

Abstract excerpt

OBJECTIVES: To determine if patients with the predominant extracranial large-vessel-vasculitis (LVV) pattern of giant cell arteritis (GCA) have a distinctive HLA-B association, different from that reported in biopsy-proven cranial GCA patients. In a further step we assessed if the combination of HLA-B and HLA-DRB1 alleles confers an increased risk for GCA susceptibility, either for the cranial and extracranial...

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PMID: 33734973
DOI: 10.55563/clinexprheumatol/nn15lt

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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