Article
Role of AmiA in the morphological transition of Helicobacter pylori and in immune escape.
PLoS pathogens - 1 Sept 2006
Chaput Catherine, Ecobichon Chantal, Cayet Nadège, Girardin Stephen E, Werts Catherine, Guadagnini Stéphanie, Prévost Marie-Christine, Mengin-Lecreulx Dominique, Labigne Agnès, Boneca Ivo G
Abstract excerpt
The human gastric pathogen Helicobacter pylori is responsible for peptic ulcers and neoplasia. Both in vitro and in the human stomach it can be found in two forms, the bacillary and coccoid forms. The molecular mechanisms of the morphological transition between these two forms and the role of coccoids remain largely unknown. The peptidoglycan (PG) layer is a major determinant of bacterial cell shape, and...
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