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Article

Impact of trisomy 8 on expression of genes located on chromosome 8 in different AML subgroups

25 Sept 2006

Abstract excerpt

Trisomy 8 is the most frequently observed trisomy in acute myeloid leukemia (AML) occurring as a sole karyotype abnormality or in addition to other chromosome aberrations. It was the aim of this study to analyze the impact of trisomy 8 on the expression of genes located on chromosome 8 in distinct AML subgroups characterized by different chromosome abnormalities in addition to trisomy 8. Gene expression analyses...

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PMID: 17001623
DOI: 10.1002/gcc.20380

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