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Molecular genetic and clinical characterization of acute myeloid leukemia with trisomy 8 as the sole chromosome abnormality.

Hematology (Amsterdam, Netherlands) - 1 Dec 2022

Liu Jie, Han WenMin, Cai Xiaohui, Wang Zheng, Cao LiuJun, Hua HaiYing, Jia ZhuXia, Chao HongYing, Lu XuZhang, Shen HongJie

Abstract excerpt

INTRODUCTION: The aim of the study was to determine molecular genetic and clinical characterization of acute myeloid leukemia (AML) with trisomy 8 as the sole chromosome abnormality, a recurrent but rare chromosomal abnormality in AML. METHODS: Interphase fluorescence in situ hybridization, reverse transcriptase-quantitative polymerase chain reaction for gene rearrangement and next-generation sequencing (NGS)...

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Share to Chromosome Aberrations
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35549661
DOI: 10.1080/16078454.2022.2071799

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