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Article

Epidermal growth factor receptor: pathway, therapies, and pipeline.

Clinical therapeutics - 1 Sept 2013

Goffin John R, Zbuk Kevin

Abstract excerpt

BACKGROUND: The epidermal growth factor receptor (EGFR) pathway is important in tumor growth, survival, and metastasis and is now the target of several therapeutic agents. OBJECTIVES: This paper seeks to review the EGFR pathway, the study and use of EGFR-directed agents in non-small-cell lung cancer (NSCLC) and colorectal cancer (CRC), and related new drug development. METHODS: PubMed was searched for...

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Source

Identifiers

PMID: 24054705
DOI: 10.1016/j.clinthera.2013.08.007

Genes

EGFR
MET
BRAF
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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