Article
Elevated mitochondrial RNA in a Chinese hamster mutant deficient in the mitochondrially encoded subunits of NADH dehydrogenase and cytochrome c oxidase.
The Journal of biological chemistry - 5 Nov 1990
Whitfield C D, Jefferson L M
Abstract excerpt
In a unique Chinese hamster mutant, Gal-32, the mitochondrially encoded subunits of cytochrome c oxidase (CO I, II, III) and NADH dehydrogenase (ND 1-6) are greatly decreased while other mitochondrially synthesized proteins, such as ATPase subunits 6 and 8, are less affected. Pulse-chase experime...
Topics
- Animals
- Cell Line
- Chromosome Mapping
- Cricetinae
- Cricetulus
- DNA Probes
- DNA, Mitochondrial
- Electron Transport Complex IV
- Female
- Macromolecular Substances
- Mitochondria
- Mutation
- NADH Dehydrogenase
- Ovary
- RNA
- RNA, Mitochondrial
- Transcription, Genetic